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Antidote for benzodiazepine toxicity10/31/2023 Keywords: Normal Pressure Hydrocephalus (NPH), VP Shunt, Stein and Langfitt Scale.īackground: Losing a baby is painful. The 78.8% patients had an excellent outcome, 17% had a good outcome and 4.2% had poor results.Ĭonclusion: Ventriculoperitoneal (VP) shunt had promising results selected on history and examination of normal pressure hydrocephalus and improved radiological in Evan’s ratio CT brain scan. 22 patients presented with dementia, 18 with urinary incontinence, 17 with gait disturbance 17, while 21 had headache based on Stein and Langfitt Scale. Results: In this study, we had 47 patients, 38 were male and 9 were female. All patients were evaluated preoperatively and compared postoperatively during 6 months duration for improvement and any associated complication. CSF was sent for microbiological and biochemical analyses. Gender distribution, presentation of symptoms and post-operative outcome based on the Stein Langfitt Scale were assessed. Patients with idiopathic normal pressure hydrocephalus (NPH) were included. Material and Methods: This study was conducted at Jinnah Postgraduate Medical Centre, a tertiary care hospital in Karachi. Objective: To determine the outcome of the ventriculoperitoneal shunt in normal pressure hydrocephalus. The antidote has a favorable risk-benet ratio when dosed appropriately and canīe a helpful diagnostic tool after ruling out the more common causes of acute sensorium loss as demonstrated by this case It also has no effect on reversing sedationĬaused by barbiturates, ethanol, or opioids. Laboratory and electrophysiological investigations were unremarkable a provisional diagnosis of drug intoxication was madeĪfter patient medication review and a trial of Flumazenil was given, after which the patient had improved dramatically.įlumazenil is not routinely used due to fears of withdrawal seizures and its high cost. A CT brain plain study wasĭone suspecting a basilar artery thrombus and he was referred to us for Neuro-Interventional procedures. He wasĮvaluated at another hospital initially and was intubated in view of his low Glasgow Coma scale. We report a case of Benzodiazepine toxicity in a 70-year-old man who presented to us in a comatose state. Due to its non-specic presentation, there is often a delay inĭiagnosis. Since its debut in the 1960s, the broad use and availability of benzodiazepines has mirrored the
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